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GU Animal Study Finds High-Fat Diet in Pregnancy Affects Generations

July 11, 2017

Researchers at Georgetown Lombardi Comprehensive Cancer Center report that feeding pregnant female mice a diet high in fat derived from common corn oil resulted in genetic changes that substantially increased breast cancer susceptibility in three generations of female offspring.

 

The study’s senior author, Leena Hilakivi-Clarke, PhD, professor of oncology at Georgetown Lombardi says, “It is believed that environmental and life-style factors, such as diet, plays a critical role in increasing human breast cancer risk, and so we use animal models to reveal the biological mechanisms responsible for the increase in risk in women and their female progeny.” 

 

A high-fat diet is linked to excess inflammation, and a number of epidemiological studies have made the connection between inflammation and risk of cancer

 

A gene screen revealed a number of genetic changes in the first (daughter) and third (great granddaughter) high-fat mice generations, including several genes linked in women to increased breast cancer risk, increased resistance to cancer treatment, poor cancer prognosis and impaired anti-cancer immunity. The researchers also found three times as many genetic changes in third generation than first generation mammary tissue between high-fat diet progeny and the control group’s offspring.

Read more here.


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Alex & Emma: At Theaters Everywhere

June 19, 2017

Alessandro Ago (Alex), son of publicist Janet Donovan and Ambasciatore Pietro Ago, married Emma Bernstein of NY and CA at the Kohl Mansion in Burlingame, CA.

 

Both an Italian and American citizen, Ago grew up in Washington, D.C. and Rome, Italy. He holds a bachelor's and master's degree from USC School of Cinematic Arts and is currently Director of Programming and Special Projects at USC and an alumni of Washington International School.

 

Emma graduated from Cornell University and also holds a Masters Degree from USC and is currently Creative Executive at Imagine Entertainment. She is the daughter of Linda Kornblau Arrick and Paul Bernstein.

 

In keeping with their cinematic interests, they created a movie poster in honor of their wedding.

 

They reside in Los Angeles, CA.


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Father's Day in The Yard

June 7, 2017

Celebrate Father's Day on Sunday, June 18th from noon unitl 3:00 pm with Bourbon & BBQ in The Yard at the Ritz-Carlton, Georgetown.

 

Come and indulge dad in a Father's Day experience he will never forget. Treat him to an afternoon of bottomless bourbon cocktails by local distiller Jos. A Magnus, selections from the grill featuring house smoked bourbon glazed ribs and locally crafted sausages, along with all the fixins' like spicy jalapeno cole slaw and fresh, homemade biscuits.

 

Cost:  $95 per adult, $45 per child under the age of 12

Tickets:  Please purchase ticket here

 

Selections from the Bar:

1 Vigilant Old Fashioned - Vigilant Gin, Campari, Grapefruit Bitters, Lizards Cherry, Antica Formula Ice Cube

2 Magnus Mule - Joseph Magnus Bourbon, Fresh Lime, Muddled Ginger, Ginger Beer, Chili Spice

3 5th Avenue - Joseph Magnus Cigar Blend Bourbon, Vintage Port, Saffron Bitters

 

Selections from the Grill:

1 Locally crafted sausages

2 Marinated skirt steak

3 House smoked bourbon glazed ribs

4 Maple BBQ chicken thighs


Fixins:

1 TJ’s Famous Mac & Cheese with Candied Bacon

2 Baked Beans

3 Spicy Jalapeno Cole Slaw

4 Dijon Potato Salad

5 The Yard’s Grilled Vegetables

6 Fresh Biscuits & Rolls

 

Sweets:

1 Bourbon Pecan Pie

2 Salted Caramel & Chocolate Cookies

3 Strawberry Shortcake


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